Cristiano Ronaldo returns to the Manchester United starting line-up tonight, after being stood down for a game by manager Erik ten Hag for refusing to come on as a substitute against Tottenham last week.
Eighteen-year-old Argentina youth international Alejandro Garnacho is handed his full debut.
Victor Lindelof partners Lisandro Martinez in central defence as Raphael Varane is injured.
Tyrell Malacia replaces Luke Shaw at left-back, whilst Harry Maguire and Donny van de Beek are on the bench after recent injuries.
Man Utd XI: De Gea, Dalot, Lindelof, Martinez, Malacia, Casemiro, Eriksen, Antony, Fernandes, Garnacho, Ronaldo.
Sheriff’s new boss Victor Mihailov makes four changes to the side that lost 3-0 at Real Sociedad last week.
Keeper Maksym Koval and Nigerian forward Iyayi Atiemwen, who was a handful for United in Moldova, are among those players who return.
Sheriff XI: Koval, Renan Guedes, Kiki, Radeljic, Kpozo, Diop, Kyabou, Mudasiru, Badolo, Akanbi, Atiemwen.
Ronaldo reaction as he returns
Cristiano Ronaldo kept his die-hard fans guessing with a positive message on social media.
After a whirlwind seven days, Ronaldo appears to be back in the good graces and is in line to reclaim his starting spot.
The 37-year-old missed United’s most recent game, a 1-1 draw against Chelsea. Because he was suspended for walking down the tunnel before full time against Tottenham Hotspur.
Ten Hag later revealed Ronaldo had turned down the opportunity to come on late in the game on October 19.
All of that appears to be in the past now. And Ronaldo is fully focused on his club’s potential next assignment, a Europa League game against Sheriff Tiraspol.
